Skip to content
Search events. View events.

All Categories

Submit Events


Click for help in using calendar displays. Print the contents of the current screen.

Advanced Search

(New Search)




Select All Deselect All

Event Details
Notify me if this event changes.Add this event to my personal calendar.Email this event to a friend.
Go Back
Biomedical Engineering Seminar Series
Start Date: 4/15/2015Start Time: 4:00 PM
End Date: 4/15/2015

Event Description:

Speaker: Rosalyn Moran, Assistant Professor, Bradley Department of Electrical & Computer Engineering, Virginia Tech

Topic: Ion Channels and Brain Connectivity in Psychosis In Vivo

Hosted by: Dr. Lilliane R. Mujica-Parodi, Department of Biomedical Engineering

Speaker's Research focus: Our research focuses on parallel aims in neuroscience: to develop new neuroimaging methodologies and to investigate the neurobiology of aging. Within the context of dynamic causal modeling—a statistical inference framework for interrogating non-invasive (functional magnetic resonance imaging, electroencephalography, and magnetoencephalography) and invasive (local field potential) neuroimages—we are developing a mathematical microscope to probe fine-grained synaptic physiological details from these macroscopic recording modalities. In the development of this technology, we rely on pharmacological, in silico, and small-animal validations and have successful initial results in humans. The approach holds promise for better understanding the active neurochemistry of brain networks that support cognition and behavior in both healthy and pathological conditions.

We are applying these techniques in combination with theoretical neurobiological constructs to investigate connectivity and synaptic physiological phenotypes of age. Specifically we are investigating whether cortical networks accrue properties such as redundancy, hyperactivation, or hypoactivation over the adult lifespan and whether particular neurotransmitters underpin such systematic changes. By investigating the neural activity supporting memory, executive function, and sensory-motor learning, we are targeting our investigations to circuits that develop pathological attributes in Alzheimer’s and Parkinson’s disease.

Our research goals are to identify potential fault lines in individual brains that may engender susceptibility to neurodegenerative disease and to produce translational imaging-based methodologies for better therapeutic interventions.
Location Information:
Laufer Center for Physical and Quantitative Biology - Laufer Center  (View Map)
100 Nicolls Rd
Stony Brook University
Stony Brook, NY 11794-5252
Room: Lecture Hall 101

Calendar Software powered by Dude Solutions   
Select item(s) to Search
Select item(s) to Search
Select item(s) to Search
Select item(s) to Search